Hmmm annoying, I found the twin witch lady people from Legend of Zelda Ocarina of Time to be annoying. I just hated going back and fourth between the two. Sure, I'd say I liked this boss, it was fun and a small challenge but annoying at the same time.
EDIT: Their official name is Twinrova if anyone cares to know :P
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I remember the witches, they always beat me when I was really young, but once I got older and stopped being an idiot I destroyed them so easily. but since practically every character in Punch-Out!! is a boss (except glass joe since beating him just proves you aren't retarded) the NES version of Soda Popinski is annoying, but really easy once you figure him out. and title-defense Bald Bull in the wii version is one of the hardest fights (and most annoying, he accounts for at least 20 of my losses) in Punch-Out history.
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Smithy from Super Mario RPG: Ledgend of teh seven stars. I hated that boss, mostly because he didn;t change much from the tank head and when he did, it was to the cat in the box head and healed himself. Took forever to beat. And Bowser from Luigi's mansion. I still can't beat him.
Johnny from Super Mairo RPG. if you kill one of his friends in battle you have to go one on one with him. UGH! the most harder boss is Bowser in Super Mairo bros. he throws hammers. lots of them and there is no way in heck to duck it
It takes an idiot to do cool things. That's why it's cool. ~Haruko Haruhara