So no matter which saved game you startup, you have no active sims in the portait panel and no household or sim information tabs? Does this happen on newly started games as well?
If you are on Patch 1.69 with the Origin tie-in, are you certain that all of the EPs you expect to have in play for these ongoing games are actually checked off on the Packs and Stuff Launcher tab and that they are actually loading?
If so, sounds like something is going wrong at the end of the startup process. Have you added any mods or CC lately that could be triggering the problem? Have you tried clearing the five cache files in your TS3 user game folder in Documents?
CasPartCache.package
compositorCache.package
scriptCache.package
simCompositorCache.package
socialCache.package (this one is optional)
And if that's no help, try pulling out your entire TS3 user game folder from Documents to the Desktop for safekeeping. The game will spawn a new one on its next attempted startup, with no added content at all and none of your prior saves, but those will all be safe back in the old folder. Can you start and run a new game that way?