Missy's career requires the Uni EP because the Science skill is a metric for job performance/advancement. Without Uni, the skill does not exist. Technically the career should work without it, but then sims will never get past Level 1 and possibly the Careers mod will start throwing errors at some point about undefined calculations.
You might try asking Missy for one that substitutes Logic for Science? She is still very much active as a content developer.