I really would like to. I wonder how it would work?

No I haven't. But it would be epic.
*poke sim* WAKE UP!
*poke sim* I wanna argue with you
*poke baby* Cuddle!

it would be more interesting than trying to play with touch pad, that's for sure! I tried playing the game once with a notebook. Not impressed.
Touch screen? Perhaps-but it would possibly not work very well-mostly because the animations would be a little hard to sync in with it.
Touch screens do well with text and other things that don't require animation. (I use one at work...and they're still fussy where you put your finger.)

Could work with some modifications. I've seen people play starcraft and Sims 1 with it. I suppose it would highly depend on what you're using, some touch screens may not be up to standards to do it though.

I don't think I'd like it playing in game - maybe I'm just too set in my ways!
Although I do quite like the idea of using it in CAS

I have a touchscreen phone and to my surprie LG or Sprint put TS3 mobile on it. I may love the sims but not the mobile version but iPhones is really good.

It probaly would be a bit annoying but I would really like to poke Sims!! Lol

I have a touch screen monitor! :D
It's pretty epic, but I really don't use it much.
It just works like a mouse(: